Ostarine, also known as MK-2866, is a selective androgen receptor modulator (SARM) that has been shown to suppress natural testosterone production in the body. SARMs like Ostarine are designed to have similar effects as anabolic steroids, but be more selective in their action. So while Ostarine builds muscle like steroids, it does not convert to estrogen or DHT, and does not appear to have as many side effects as traditional steroids.
However, one downside of SARMs like Ostarine is that they can still suppress or even shut down your natural testosterone production. Numerous studies have shown that Ostarine will lower total testosterone levels in the body after a cycle. One clinical trial found that a 3 mg per day dosage of Ostarine for 4 weeks lowered total testosterone by 70% on average.
The degree of testosterone suppression appears to be dose-dependent. Higher daily dosages and longer cycle lengths will increase testosterone suppression from Ostarine. However, even at lower doses, Ostarine is very likely to cause some degree of hypogonadism and testosterone shutdown.
Symptoms of low testosterone from Ostarine use can include:
- Decreased libido
- Erectile dysfunction
- Fatigue
- Loss of muscle mass
- Increased body fat
- Depression
To counteract testosterone suppression from Ostarine, it is recommended to do a proper post cycle therapy (PCT) protocol after your cycle. A SERM like Nolvadex or Clomid is commonly used for 3-6 weeks to help kickstart your natural testosterone production again.
Without a proper PCT, it may take many months for your testosterone levels to recover from an Ostarine cycle. Some bodybuilders have reported low testosterone symptoms persisting for 6-12 months after using Ostarine without a PCT.
So in summary - yes, Ostarine will very likely cause partial or total shutdown of your body's natural testosterone production depending on the dosage and cycle length. Make sure you get pre and post-cycle bloodwork to monitor your hormone levels. And implement an effective PCT plan, focusing on testosterone recovery supplements, to minimize shutdown and get your T levels back to normal faster.
At Hormone Harmony Clinic, we specialize in hormone optimization, testing, and post-cycle therapy for performance enhancement and anti-aging. Our highly trained hormone doctors can help make sure you maintain healthy testosterone levels before, during and after any SARM or steroid cycle. We offer comprehensive bloodwork panels, pharmaceutical grade medications and supplements, and expert medical guidance.
Visit us at to learn more about our men's health, hormone balance and PCT programs. We offer individualized treatment plans, telemedicine services, and convenient nationwide shipping of all medication and supplements right to your door.
Maintaining proper hormone balance is key for health, wellbeing and physique goals. Don't wait until after you've started a cycle to get your hormone levels tested. Be proactive by partnering with a clinic like Hormone Harmony Clinic first, so you can minimize side effects and maximize your results in a safe, legal and supervised manner. We're here to help guide you on your physique and performance enhancing journey every step of the way!